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The book discusses the notion of time (reversible vs. irreversible), gives a mathematical overview of transformation groups and statistical mechanics (Gibbs style), time series, information and communication (Shannon style), explores feedback and stability of systems containing feedback, and then goes on by trying to apply all that to understanding how organisms and brains work.

It apparently is a classic book, and most likely was state-of-the-art, innovative and influential when it first came out in 1948. However, I, in 2007, did not much enjoy reading it as most of the content is nowadays either well known or disproven. What I did get out of it was a quick glimpse into the state of science more than half a century ago.

More information at Amazon: http://www.amazon.com/dp/026273009X